Use proportion of samples for which a mass/peak is present to compare two groups and determine which peaks are uniquely expressed in each group

uniqueness_prop(edata_df, group_df, data_scale, pres_thresh, absn_thresh)

Arguments

edata_df

data.frame giving samples expression profiles for samples belonging to one of two groups

group_df

data.frame giving sample names and column indicating group membership. Column indicating group membership should be named 'Group' and have exactly two unique values

data_scale

character string giving scale the data is on. Current acceptable values are: "log", "log2", "log10", "abundance", "pres"

pres_thresh

numeric value between 0 and 1, inclusive, indicating the minimum proportion of samples per group that are required for a peak to be considered present/observed in a group.

absn_thresh

numeric value between 0 and 1, inclusive, indicating the maximum proportion of samples per group that can be observed for a peak to be considered absent in a group.

Author

Lisa Bramer